The Universal Islamic Declaration on Human Rights (the UIDHR) is the most important official replication to the Universal Declaration of Human Rights (the UDHR) by Islamic countries, and based on that, it has been attempted to provide a declaration containing the benefits of the UDHR and at the same time devoid of its faults. However, a detailed study of the UIDHR makes us uncertain in achieving these objectives. In this study, after a brief introduction of the history and development of the provisions of the UIDHR, incompatible cases with the provisions of the UDHR are reported, some inequalities of rights between men and women are recognized and arguments in favor of it are mentioned, interpreted and analyzed. It appears that the UIDHR, as an universal document, which seeks to ensure human rights, carries three major drawbacks; first, implicit approval of some of inequalities of rights between men and women based on gender and religion; second, fluid and variable interpretative sources; third, lack of sanction. These three problems have diminished the reputation of this declaration and changed it to a number of non-binding ethical recommendations.